Esophageal cancerIntroduction

 Keeping serum 25-hydroxyvitamin D levels above 40 ng/mL might reduce incidence by 20-25% and increase survival after diagnosis.

Esophageal cancer is one of the approximately 20 vitamin D-sensitive types of cancer. The evidence comes largely from ecological (geographical) studies of esophageal cancer mortality rates.

Based on analogy with the geographical variation of breast cancer mortality rates as well as observational studies for breast and colorectal cancer incidence, it appears that keeping serum 25-hydroxyvitamin D levels above 40 ng/mL might reduce incidence by 20-25% and increase survival after diagnosis.

Calcium intake also seems to reduce risk12

Page last edited: 22 August 2011

References

  1. Wolfgarten, E. Rosendahl, U. Nowroth, T. Leers, J. Metzger, R. Holscher, A. H. Bollschweiler, E. Coincidence of nutritional habits and esophageal cancer in Germany. Onkologie. 2001 Dec; 24 (6): 546-51.
  2. Peterlik, M. Grant, W. B. Cross, H. S. Calcium, vitamin D and cancer. Anticancer Res. 2009 Sep; 29 (9): 3687-98.