Gastric cancerTreatment

There is no experimental evidence that vitamin D can be used to treat gastric cancer.

There are no results for treating gastric cancer with vitamin D.

Based on analogy with the geographical variation of breast, colon, and rectal cancer mortality rates, and observational studies of incidence of breast and colorectal cancer1, and the increased survival for those with higher serum 25(OH)D levels after diagnosis of several types of cancer, it seems that keeping serum 25(OH)D levels above 40-60 ng/mL might reduce risk by 25-35% and increase survival after diagnosis.

Studies on serum 25(OH)D levels at time of diagnosis of breast2 found that those with higher levels (>30 ng/mL) had about twice the 12-year survival rate of those with lower levels. Similar results were found for colorectal cancer3. See additional references in Shanafelt4.

Page last edited: 22 August 2011

References

  1. Grant, W. B. Relation between prediagnostic serum 25-hydroxyvitamin D level and incidence of breast, colorectal, and other cancers. J Photochem Photobiol B. 2010 May 12;
  2. Goodwin, P. J. et al. Frequency of vitamin D (Vit D) deficiency at breast cancer (BC) diagnosis and association with risk of distant recurrence and death in a prospective cohort study of T1-3, N0-1, M0 BC. J Clin Oncol. 2008 May; 20511.
  3. Ng, K. Wolpin, B. M. Meyerhardt, J. A. Wu, K. Chan, A. T. Hollis, B. W. Giovannucci, E. L. Stampfer, M. J. Willett, W. C. Fuchs, C. S. Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer. Br J Cancer. 2009 Sep 15; 101 (6): 916-23.
  4. Shanafelt, T. D. Drake, M. T. Maurer, M. J. Allmer, C. Rabe, K. G. Slager, S. L. Weiner, G. J. Call, T. G. Link, B. K. Zent, C. S. Kay, N. E. Hanson, C. A. Witzig, T. E. Cerhan, J. R. Vitamin D insufficiency and prognosis in chronic lymphocytic leukemia (CLL). Blood. 2010 Nov 3;