Based on the ecological studies of lung cancer mortality rates with respect to solar UVB indices, and observational studies of incidence of breast and colorectal cancer1, it appears that serum 25(OH)D levels above 40 ng/mL (100 nmol/L) throughout life might reduce the risk of developing lung cancer by perhaps 25-35%.
However, it is noted that smokers generally have lower 25(OH)D levels than nonsmokers1 as well as higher parathyroid hormone levels2, so they should probably supplement with higher amounts than nonsmokers.
Page last edited: 18 July 2011
- Brot, C. Jorgensen, N. R. Sorensen, O. H. The influence of smoking on vitamin D status and calcium metabolism. Eur J Clin Nutr. 1999 Dec; 53 (12): 920-6.
- Jorde, R. Saleh, F. Figenschau, Y. Kamycheva, E. Haug, E. Sundsfjord, J. Serum parathyroid hormone (PTH) levels in smokers and non-smokers. The fifth Tromsø study. Eur J Endocrinol. 2005 Jan.; 52 (1): 39-45.