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Anyone considered at risk for or presenting with cardiovascular disease (CVD) should strongly consider increasing serum 25(OH)D levels to somewhere in the 40-80 ng/mL range.
Serum 25(OH)D levels can be estimated based on a number of factors including oral intake and vitamin D production from solar UVB, but for certainty, serum 25(OH)D levels can be measured.
Each 1000 IU/day of vitamin D3 increases serum 25(OH)D levels by 6-10 ng/mL1. Doses as high as 50,000 IU/day can be taken for a few days to bring serum 25(OH)D levels up rapidly.
Page last edited: 04 May 2011
- Heaney, R. P. Davies, K. M. Chen, T. C. Holick, M. F. Barger-Lux, M. J. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr. 2003 Jan; 77 (1): 204-10.