There is one reported randomized controlled study of vitamin D supplementation and risk of preeclampsia, performed in Norway on nulliporos women:
The odds ratio of preeclampsia for women with a total vitamin D intake of 15-20 microg/d compared with less than 5 microg/d was 0.76 (95% confidence interval = 0.60-0.95). Considering only the intake of vitamin D from supplements, we found a 27% reduction in risk of preeclampsia (OR = 0.73 [0.58-0.92]) for women taking 10-15 microg/d as compared with no supplements. No association was found between intake of vitamin D from the diet alone and the occurrence of preeclampsia3. (1 microg/d = 40 IU/d).
Based on the findings by Bodnar et al4 it appears that serum 25(OH)D levels should be kept above 40 ng/ml during pregnancy. Pregnant women should consider taking several thousand IU/day of vitamin D35.
Page last edited: 03 May 2011
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